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TAS2R45
Identifiers
Aliases	TAS2R45 , GPR59, T2R45, ZG24P, taste 2 receptor member 45
External IDs	OMIM: 613967; GeneCards: TAS2R45; OMA:TAS2R45 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	11,184,006 bp
Gene ontology
Molecular function	G protein-coupled receptor activity ; signal transducer activity ; bitter taste receptor activity ;
Cellular component	integral component of membrane ; plasma membrane ; membrane ;
Biological process	detection of chemical stimulus involved in sensory perception of bitter taste ; signal transduction ; response to stimulus ; sensory perception of taste ; G protein-coupled receptor signaling pathway ;
	Sources:Amigo / QuickGO
Orthologs
	259291
	n/a
	ENSG00000261936
	n/a
	P59539
	n/a
	NM_176886
	n/a
	NP_795367
	n/a
	Wikidata
View/Edit Human

TAS2R45

Last updated July 17, 2025

Taste receptor type 2 member 45 is a protein that in humans is encoded by the TAS2R45 gene.^[2]^[3]

References

↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
↑ "Entrez Gene: TAS2R45 taste receptor, type 2, member 45".

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi: 10.1074/jbc.R100054200 . PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi: 10.1016/S0092-8674(03)00071-0 . PMID 12581520. S2CID 718601.
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719 . PMID 15744053.

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[1] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12379855-2] Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.

[entrez-3] "Entrez Gene: TAS2R45 taste receptor, type 2, member 45".

[1]

[2]

[3]

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TAS2R45

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