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YBX3
Identifiers
Aliases	YBX3 , CSDA, CSDA1, DBPA, ZONAB, Y-box binding protein 3
External IDs	OMIM: 603437; MGI: 2137670; HomoloGene: 2708; GeneCards: YBX3; OMA:YBX3 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	10,723,323 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	131,365,439 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; Skeletal muscle tissue of rectus abdominis; ; muscle of thigh; ; body of tongue; ; Skeletal muscle tissue of biceps brachii; ; vastus lateralis muscle; ; tibialis anterior muscle; ; deltoid muscle; ; triceps brachii muscle; ; thoracic diaphragm;
	Top expressed in
	seminiferous tubule; ; blood; ; medial head of gastrocnemius muscle; ; external carotid artery; ; internal carotid artery; ; muscle of thigh; ; quadriceps femoris muscle; ; intercostal muscle; ; digastric muscle; ; hair follicle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding ; RNA polymerase II transcription regulatory region sequence-specific DNA binding ; transcription corepressor activity ; DNA-binding transcription factor activity ; mRNA 3'-UTR binding ; single-stranded DNA binding ; DNA-binding transcription repressor activity, RNA polymerase II-specific ; nucleic acid binding ; double-stranded DNA binding ; RNA binding ; DNA-binding transcription factor activity, RNA polymerase II-specific ; protein binding ; polysome binding ;
Cellular component	polysome ; bicellular tight junction ; perinuclear region of cytoplasm ; nucleus ; cytoplasm ; cytosol ;
Biological process	male gonad development ; regulation of transcription, DNA-templated ; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress ; negative regulation of necroptotic process ; positive regulation of cytoplasmic translation ; cellular response to tumor necrosis factor ; positive regulation of organ growth ; negative regulation of apoptotic process ; in utero embryonic development ; negative regulation of transcription by RNA polymerase II ; transcription, DNA-templated ; cellular hyperosmotic response ; negative regulation of skeletal muscle tissue development ; spermatogenesis ; response to cold ; fertilization ; 3'-UTR-mediated mRNA stabilization ;
	Sources:Amigo / QuickGO
Orthologs
	8531
	56449
	ENSG00000060138
	ENSMUSG00000030189
	P16989
	Q9JKB3
	NM_001145426 ; NM_003651
	NM_011733 ; NM_139117
	NP_001138898 ; NP_003642
	NP_035863 ; NP_620817
	Wikidata
View/Edit Human	View/Edit Mouse

CSDA (gene)

Last updated November 14, 2025

DNA-binding protein A is a protein that in humans is encoded by the CSDA gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000060138 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030189 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Sakura H, Maekawa T, Imamoto F, Yasuda K, Ishii S (Jun 1989). "Two human genes isolated by a novel method encode DNA-binding proteins containing a common region of homology". Gene. 73 (2): 499–507. doi:10.1016/0378-1119(88)90514-8. PMID 2977358.
↑ Coles LS, Diamond P, Occhiodoro F, Vadas MA, Shannon MF (Sep 1996). "Cold shock domain proteins repress transcription from the GM-CSF promoter". Nucleic Acids Res. 24 (12): 2311–7. doi:10.1093/nar/24.12.2311. PMC 145951 . PMID 8710501.
↑ "Entrez Gene: CSDA cold shock domain protein A".

External links

CSDA+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Human YBX3 genome location and YBX3 gene details page in the UCSC Genome Browser .

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000060138 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030189 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2977358-5] Sakura H, Maekawa T, Imamoto F, Yasuda K, Ishii S (Jun 1989). "Two human genes isolated by a novel method encode DNA-binding proteins containing a common region of homology". Gene. 73 (2): 499–507. doi:10.1016/0378-1119(88)90514-8. PMID 2977358.

[pmid8710501-6] Coles LS, Diamond P, Occhiodoro F, Vadas MA, Shannon MF (Sep 1996). "Cold shock domain proteins repress transcription from the GM-CSF promoter". Nucleic Acids Res. 24 (12): 2311–7. doi:10.1093/nar/24.12.2311. PMC 145951 . PMID 8710501.

[entrez-7] "Entrez Gene: CSDA cold shock domain protein A".

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CSDA (gene)

Contents

References

Further reading

External links