Montefiore Medical Center is a premier academic medical center and the primary teaching hospital of the Albert Einstein College of Medicine in the Bronx, New York City. Its main campus, the Henry and Lucy Moses Division, is located in the Norwood section of the northern Bronx. It is named for Moses Montefiore and is one of the 50 largest employers in New York. In 2020, Montefiore was ranked No. 6 New York City metropolitan area hospitals by U.S. News & World Report. Adjacent to the main hospital is the Children's Hospital at Montefiore, which serves infants, children, teens, and young adults aged 0-21.

Jacobi Medical Center is a municipal hospital operated by NYC Health + Hospitals in affiliation with the Albert Einstein College of Medicine. The facility is located in the Morris Park neighborhood of the Bronx, New York City. It is named in honor of German physician Abraham Jacobi, who is regarded as the father of American pediatrics.

Saint Vincent Catholic Medical Centers was a healthcare system, anchored by its flagship hospital, St. Vincent's Hospital Manhattan, locally referred to as "St. Vincent's". St. Vincent's was founded in 1849 and was a major teaching hospital in the Greenwich Village neighborhood of Manhattan, New York City. It closed on April 30, 2010, under circumstances that triggered an investigation by the Manhattan District Attorney. Demolition began at the end of 2012 and was completed in early 2013. Other hospital buildings are being converted into luxury condos and a new luxury building, Greenwich Lane, has replaced the St. Vincent's building.

Calvary Hospital is an American non-profit institution specializing in hospice and palliative care, headquartered in the Bronx, a borough of New York City, New York. The hospital has a total of 225 beds.

The BronxCare Health System, previously known as "Bronx-Lebanon Hospital Center," is a hospital in the Bronx, New York City. It was founded as the Lebanon Hospital by Jonas Weil in 1890. In 1962, Lebanon Hospital merged with Bronx Hospital, and since 2016 the combined center has served as a teaching hospital for Mount Sinai School of Medicine.

NYC Health + Hospitals/North Central Bronx, better known as North Central Bronx Hospital, is a municipal hospital founded in 1976 and operated by NYC Health + Hospitals. The 17 story Brutalist style building is located next to the Montefiore Medical Center in the Norwood neighborhood of The Bronx in New York City.

St Barnabas Hospital is a non-profit teaching hospital founded in 1866. The hospital is located in the Belmont neighborhood of The Bronx in New York City. It is a level II adult trauma center and is a major clinical affiliate for clinical clerkship of the New York Institute of Technology College of Osteopathic Medicine.

The James J. Peters VA Medical Center,, is a US Department of Veterans Affairs hospital complex located at 130 West Kingsbridge Road in West Fordham, Bronx, New York City. The hospital is the headquarters of the Veterans Integrated Service Networks New York/New Jersey VA Health Care Network. This network is also the parent network to VA New York Harbor Healthcare System.

U.S. Army General Hospital No. 1, also known as Columbia War Hospital, was a World War I era field hospital built by Columbia University on the Columbia Oval property in Norwood, The Bronx. The hospital was used as a medical training facility, a model for military field hospitals, and for long-term treatment of patients.

Westchester Square Medical Center, located in Westchester Square, opened in 1930 as Westchester Square Hospital, and currently houses an emergency room, operating rooms, and offices for Montefiore Medical Center.

Beth Abraham Center for Rehabilitation and Nursing is a medical facility in Bronx, New York, which was founded as the Beth Abraham Home for Incurables. It was originally a long-term residential care facility, but was later expanded to include rehabilitation services.