英文互译镜像站

Quinoline 2-oxidoreductase

Last updated
quinoline 2-oxidoreductase
Identifiers
EC no. 1.3.99.17
CAS no. 132264-32-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, quinoline 2-oxidoreductase (EC 1.3.99.17) is an enzyme that catalyzes the chemical reaction

 
H2O
 
Quinoline 2-oxidoreductase
H2O
 
 
+ reduced acceptor
 

The three substrates of this enzyme are quinoline, an electron acceptor, and water. Its products are 2-quinolone and reduced acceptor. [1] [2] [3] [4]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is quinoline:acceptor 2-oxidoreductase (hydroxylating).

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1T3Q.

References

  1. Enzyme 1.3.99.17 at KEGG Pathway Database.
  2. Bauder, Renate; Tshisuaka, Barbara; Lingens, Franz (1990). "Microbial Metabolism of Quinoline and Related Compounds. VII. Quinoline Oxidoreductase from Pseudomonas putida: A Molybdenum-Containing Enzyme". Biological Chemistry Hoppe-Seyler. 371 (2): 1137–1144. doi:10.1515/bchm3.1990.371.2.1137. PMID   2090161.
  3. Peschke, Bernd; Lingens, Franz (1991). "Microbial Metabolism of Quinoline and Related Compounds. XII. Isolation and Characterization of the Quinoline Oxidoreductase from Rhodococcus spec. B1 Compared with the Quinoline Oxidoreductase from Pseudomonas putida 86". Biological Chemistry Hoppe-Seyler. 372 (2): 1081–1088. doi:10.1515/bchm3.1991.372.2.1081. PMID   1789933.
  4. Schach, Susanne; Tshisuaka, Barbara; Fetzner, Susanne; Lingens, Franz (1995). "Quinoline 2-oxidoreductase and 2-oxo-1,2-dihydroquinoline 5,6-dioxygenase from Comamonas testosteroni 63. The First Two Enzymes in Quinoline and 3-methylquinoline Degradation". European Journal of Biochemistry. 232 (2): 536–544. doi: 10.1111/j.1432-1033.1995.536zz.x .


站群克隆软件 蚪侠镜像站群 MirrorElfR 一键镜像站群 镜像软件