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Quinoline-4-carboxylate 2-oxidoreductase

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quinoline-4-carboxylate 2-oxidoreductase
Identifiers
EC no. 1.3.99.19
CAS no. 175780-18-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, quinoline-4-carboxylate 2-oxidoreductase (EC 1.3.99.19) is an enzyme that catalyzes the chemical reaction

 
H2O
 
Quinoline-4-carboxylate 2-oxidoreductase
H2O
 
 
+ reduced acceptor
 

The three substrates of this enzyme are quinoline-4-carboxylic acid, an electron acceptor, and water. Its products are 2-hydroxycinchoninic acid and reduced acceptor. [1] [2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating). Other names in common use include quinaldic acid 4-oxidoreductase, and quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating).

References

  1. Enzyme 1.3.99.19 at KEGG Pathway Database.
  2. Bauer G, Lingens F (1992). "Microbial metabolism of quinoline and related compounds. XV Quinoline-4-carboxylic acid oxidoreductase from Agrobacterium spec.1B: a molybdenum-containing enzyme". Biol. Chem. Hoppe-Seyler. 373 (8): 699–705. doi:10.1515/bchm3.1992.373.2.699. PMID   1418685.


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