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Pseudooxynicotine oxidase

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Pseudooxynicotine oxidase
Identifiers
EC no. 1.4.2.3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

Pseudooxynicotine oxidase (EC 1.4.2.3) is an enzyme with systematic name 4-(methylamino)-1-(pyridin-3-yl)butan-1-one:oxygen oxidoreductase (methylamine releasing). [1] This enzyme catalyses the following chemical reaction

 
H2O
2 H+
Pseudooxynicotine oxidase
H2O
2 H+
 
+ 2 ferrocytochrome c + CH3NH2
 

This enzyme contains one non-covalently bound flavin adenine dinucleotide. It is involved in nicotine breakdown in soil bacteria and releases methylamine. [2]

References

  1. Qiu J, Ma Y, Wen Y, Chen L, Wu L, Liu W (April 2012). "Functional identification of two novel genes from Pseudomonas sp. strain HZN6 involved in the catabolism of nicotine". Applied and Environmental Microbiology. 78 (7): 2154–60. Bibcode:2012ApEnM..78.2154Q. doi:10.1128/AEM.07025-11. PMC   3302611 . PMID   22267672.
  2. Enzyme 1.4.2.3 at KEGG Pathway Database.
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