| phthalate 4,5-cis-dihydrodiol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.1.64 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, phthalate 4,5-cis-dihydrodiol dehydrogenase (EC 1.3.1.64) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylic acid and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 4,5-dihydroxyphthalic acid, reduced NADH, and a proton. [1] [2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase. This enzyme participates in 2,4-dichlorobenzoate degradation.
