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mir-326
mir-326
Identifiers
Symbol	mir-326
Rfam	RF00719
miRBase family	MIPF0000143
Other data
RNA type	microRNA
Domain	Eukaryota;
PDB structures	PDBe

Mir-326 microRNA precursor family

Last updated October 08, 2025

In molecular biology mir-326 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

References

D'Angelo D, Palmieri D, Mussnich P, Roche M, Wierinckx A, Raverot G, Fedele M, Croce CM, Trouillas J, Fusco A (July 2012). "Altered microRNA expression profile in human pituitary GH adenomas: down-regulation of miRNA targeting HMGA1, HMGA2, and E2F1". The Journal of Clinical Endocrinology and Metabolism. 97 (7): E1128-38. doi: 10.1210/jc.2011-3482 . PMID 22564666.
Hamada N, Fujita Y, Kojima T, Kitamoto A, Akao Y, Nozawa Y, Ito M (June 2012). "MicroRNA expression profiling of NGF-treated PC12 cells revealed a critical role for miR-221 in neuronal differentiation". Neurochemistry International. 60 (8): 743–50. doi:10.1016/j.neuint.2012.03.010. PMID 22465943. S2CID 40247078.
Sebastiani G, Grieco FA, Spagnuolo I, Galleri L, Cataldo D, Dotta F (November 2011). "Increased expression of microRNA miR-326 in type 1 diabetic patients with ongoing islet autoimmunity". Diabetes/Metabolism Research and Reviews. 27 (8): 862–6. doi:10.1002/dmrr.1262. PMID 22069274. S2CID 29304855.
Schaefer JS, Montufar-Solis D, Vigneswaran N, Klein JR (December 2011). "Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-10-/- mice precedes expression in the colon". Journal of Immunology. 187 (11): 5834–41. doi:10.4049/jimmunol.1100922. PMC 3221883 . PMID 22043014.
Waschbisch A, Atiya M, Linker RA, Potapov S, Schwab S, Derfuss T (2011). Kleinschnitz C (ed.). "Glatiramer acetate treatment normalizes deregulated microRNA expression in relapsing remitting multiple sclerosis". PLOS ONE. 6 (9) e24604. Bibcode:2011PLoSO...624604W. doi: 10.1371/journal.pone.0024604 . PMC 3174971 . PMID 21949733.
Ralfkiaer U, Hagedorn PH, Bangsgaard N, Løvendorf MB, Ahler CB, Svensson L, Kopp KL, Vennegaard MT, Lauenborg B, Zibert JR, Krejsgaard T, Bonefeld CM, Søkilde R, Gjerdrum LM, Labuda T, Mathiesen AM, Grønbæk K, Wasik MA, Sokolowska-Wojdylo M, Queille-Roussel C, Gniadecki R, Ralfkiaer E, Geisler C, Litman T, Woetmann A, Glue C, Røpke MA, Skov L, Odum N (November 2011). "Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)". Blood. 118 (22): 5891–900. doi:10.1182/blood-2011-06-358382. PMC 3342856 . PMID 21865341.
Junker A (December 2011). "Pathophysiology of translational regulation by microRNAs in multiple sclerosis". FEBS Letters. 585 (23): 3738–46. Bibcode:2011FEBSL.585.3738J. doi: 10.1016/j.febslet.2011.03.052 . PMID 21453702.
Kefas B, Comeau L, Erdle N, Montgomery E, Amos S, Purow B (November 2010). "Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells". Neuro-Oncology. 12 (11): 1102–12. doi:10.1093/neuonc/noq080. PMC 3098027 . PMID 20667897.
Kefas B, Comeau L, Floyd DH, Seleverstov O, Godlewski J, Schmittgen T, Jiang J, diPierro CG, Li Y, Chiocca EA, Lee J, Fine H, Abounader R, Lawler S, Purow B (December 2009). "The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors". The Journal of Neuroscience. 29 (48): 15161–8. doi:10.1523/JNEUROSCI.4966-09.2009. PMC 2823067 . PMID 19955368.
Liang Z, Wu H, Xia J, Li Y, Zhang Y, Huang K, Wagar N, Yoon Y, Cho HT, Scala S, Shim H (March 2010). "Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1". Biochemical Pharmacology. 79 (6): 817–24. doi:10.1016/j.bcp.2009.10.017. PMC 2880168 . PMID 19883630.
Du C, Liu C, Kang J, Zhao G, Ye Z, Huang S, Li Z, Wu Z, Pei G (December 2009). "MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis". Nature Immunology. 10 (12): 1252–9. doi:10.1038/ni.1798. PMID 19838199. S2CID 15500858.
Xu CF, Yu CH, Li YM (December 2009). "Regulation of hepatic microRNA expression in response to ischemic preconditioning following ischemia/reperfusion injury in mice". OMICS. 13 (6): 513–20. doi:10.1089/omi.2009.0035. PMID 19780683.
Tang YF, Zhang Y, Li XY, Li C, Tian W, Liu L (August 2009). "Expression of miR-31, miR-125b-5p, and miR-326 in the adipogenic differentiation process of adipose-derived stem cells". OMICS. 13 (4): 331–6. doi:10.1089/omi.2009.0017. PMID 19422302.
Ferretti E, De Smaele E, Miele E, Laneve P, Po A, Pelloni M, Paganelli A, Di Marcotullio L, Caffarelli E, Screpanti I, Bozzoni I, Gulino A (October 2008). "Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells". The EMBO Journal. 27 (19): 2616–27. doi:10.1038/emboj.2008.172. PMC 2567402 . PMID 18756266.

External links

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v t e miRNA precursor families
1-100	1 2 3 5 6 7 8/141/200 9/79 10 11 14 15 16 17 19 21 22 23 24 25 26 28 29 30 31 32 33 34 42 46/47/281 48 52 58 61 62 67 71 84 92 96
101-200	101 103/107 122 124 126 127 129 130 132 133 134 135 137 138 141 143 144 145 146 148/152 150 153 154 155 156 160 166 172 181 184 185 186 187 188 190 191 192/215 193 194 196 198 199 200
201-300	202 203 203a 205 208 210 212 214 216 218 219 221 223 224 241 275 277 278 279 281 282 296 299
301-400	301 305 322 326 330 331 337 338 339 340 344 345 346 350 351 361 363 365 367 370 374 383 384 390 394 395 396 397 398 399
401-500	403 408 423 425 430 431 432 433 434 444 448 449 451 452 454 455 474 484 488 489 491 492 497 498 500
501-600	503 504 505 506 529 535 541 542 544 548 549 550 552 558 562 569 572 575 580 584 589 590 592 598
601+	601 605 612 615 612 612 624 625 632 633 636 638 650 652 657 661 663 671 672 675 708 711 720 744 764 765 767 786 802 824 828 854 872 873 874 885 938 939 3180
Other	BART1 BART2 BHRF1-1 BHRF1-2 BHRF1-3 Let-7 Lin-4 Lsy-6

英文互译镜像站

Mir-326 microRNA precursor family

Contents

See also

References

Further reading

External links