These are the Billboard magazine Dance/Mix Show Airplay number-one hits of 2022.
| † | Indicates best charting dance/mix show airplay single of 2022 Note: Year-end most popular songs based radio airplay. [1] |
| Issue date | Song | Artist(s) | Remixer(s) | Ref(s) |
|---|---|---|---|---|
| January 1 | "Cold Heart" | Elton John and Dua Lipa | Pnau, PS1 | [2] |
| January 8 | [3] | |||
| January 15 | [4] | |||
| January 22 | [5] | |||
| January 29 | [6] | |||
| February 5 | "Tell It to My Heart" | Meduza featuring Hozier | Tiesto, Kream, James Hype | [7] |
| February 12 | "The Motto" | Tiësto and Ava Max | Juez, New Road & DVNIAR | [8] |
| February 19 | [9] | |||
| February 26 | "High" | The Chainsmokers | Don Diablo, Crankdat, Leondis, Baddies Only, Star Seed | [10] |
| March 5 | [11] | |||
| March 12 | [12] | |||
| March 19 | [13] | |||
| March 26 | [14] | |||
| April 2 | [15] | |||
| April 9 | "Don't Forget My Love" | Diplo and Miguel | John Summit, Burns, Joel Corry | [16] |
| April 16 | [17] | |||
| April 23 | "Escape" | Kx5 Featuring Hayla | John Summit, Spencer Brown | [18] |
| April 30 | [19] | |||
| May 7 | [20] | |||
| May 14 | [21] | |||
| May 21 | [22] | |||
| May 28 | [23] | |||
| June 4 | [24] | |||
| June 11 | [25] | |||
| June 18 | "As It Was"† | Harry Styles | Thnked, Phrase, Minlee | [26] |
| June 25 | [27] | |||
| July 2 | " About Damn Time" | Lizzo | Purple Disco Machine, David Michael | [28] |
| July 9 | [29] | |||
| July 16 | [30] | |||
| July 23 | [31] | |||
| July 30 | [32] | |||
| August 6 | "Break My Soul" | Beyoncé | Terry Hunter, Essential Bounce | [33] |
| August 13 | [34] | |||
| August 20 | [35] | |||
| August 27 | [36] | |||
| September 3 | [37] | |||
| September 10 | "Deep Down" | Alok, Ella Eyre and Kenny Dope featuring Never Dull | Paul Mayson | [38] |
| September 17 | [39] | |||
| September 24 | [40] | |||
| October 1 | [41] | |||
| October 8 | "Hold Me Closer" | Elton John and Britney Spears | Purple Disco Machine,Joel Corry, MIB Project | [42] |
| October 15 | [43] | |||
| October 22 | [44] | |||
| October 29 | "I'm Good (Blue)" | David Guetta and Bebe Rexha | Oliver Heldens, Tiësto, R3hab | [45] |
| November 5 | [46] | |||
| November 12 | [47] | |||
| November 19 | [48] | |||
| November 26 | [49] | |||
| December 3 | "Unholy" | Sam Smith and Kim Petras | Acraze, Disclosure, Dxrk, Nova Twins | [50] |
| December 10 | [51] | |||
| December 17 | [52] | |||
| December 24 | "I'm Good (Blue)" | David Guetta and Bebe Rexha | Oliver Heldens, Tiësto, R3hab | [53] |
| December 31 | [54] |
Dance/Mix Show Airplay is a monitored electronic dance music radio chart that is published weekly by Billboard magazine.
From October 26, 1974 until August 28, 1976, Billboard's Disco Action section published weekly single retail sales charts from various local regions along with Top Audience Response Records in their magazine. Billboard debuted its first national chart devoted exclusively to 12-inch Singles Sales in their issue dated March 16, 1985. This record type is most commonly used in disco and dance music genres where DJs use them to play in discos or dance clubs because of the exclusive extended remixes that are often only made available on this format, but Billboard's 12-inch Single Sales chart ranks releases by artists from all styles of music that release maxi-singles.
Throughout his career, Dutch electronic DJ and producer Tiësto has released seven studio albums. After spending years searching for his personal style and working with DJs like Ferry Corsten, Benno de Goeij and Armin van Buuren, he decided it was time to focus on his solo work. Tiësto's fame started to rise in the late 1990s after his set at the first ID&T Innercity party, and it continued to skyrocket in the early 2000s following his six-hour "Tiësto Solo" sets, which he performed without any other DJs or opening acts. His last three full-length releases broke the 70,000-unit mark, and the 2003 DJ mix Nyana hit 87,000, according to Nielsen SoundScan in mid-2008.

"Ghosts 'n' Stuff" is an electro house song by Canadian electronic music producer Deadmau5 featuring vocals by Australian producer Rob Swire. Its instrumental was released as a single on October 27, 2008, and re-released with vocals on September 27, 2009. The latter was featured on Deadmau5's fourth studio album For Lack of a Better Name.
CamelPhat are an English DJ and production duo, consisting of Dave Whelan and Mike Di Scala, formed in Liverpool in 2006.

"Believer" is a song by American pop rock band Imagine Dragons. The song was released on February 1, 2017, through Interscope Records and Kidinakorner as the lead single from the band's third studio album, Evolve (2017). It was written by Dan Reynolds, Wayne Sermon, Ben McKee, Daniel Platzman, Justin Tranter, Jamie marcel and its producers Mattman & Robin.

"Feel It Still" is a song by American rock band Portugal. The Man. The song draws on the melody from the Marvelettes' 1961 hit "Please Mr. Postman"; written by the band along with producers John Hill and Asa Taccone, "Feel It Still" also includes a credit for Motown songwriter Brian Holland. It serves as the second single and first radio single off their eighth studio album, Woodstock. The song reached number one on the US Alternative Songs, Mexican and Russian Tophit airplay chart. It was also their first entry on the US Billboard Hot 100, becoming a sleeper hit, as it took eight months to peak at number four in November 2017.

"Havana" is a song by American singer and songwriter Camila Cabello from her debut studio album Camila (2018). Featuring American rapper Young Thug, it was released on August 3, 2017, alongside "OMG" initially as a promotional single; it was later serviced to radio on September 8, 2017, as a single. Due to its rising success, "Havana" later became the official lead single of Camila, replacing "Crying in the Club".

"Dance Monkey" is a song by Australian singer Tones and I, released on 10 May 2019 as the second single from Tones and I's debut EP, The Kids Are Coming. The song was produced and mixed by Konstantin Kersting.

"Circles" is a song by American rapper and singer Post Malone. It was released through Republic Records on August 30, 2019, as the third single from Malone's third studio album Hollywood's Bleeding (2019). It reached number one on the US Billboard Hot 100 for the week of November 30, 2019, topping the chart for three weeks, marking Post Malone's fourth number-one song, as well as his first solo effort to top the chart. The song also reached number one in Iceland, Malaysia, and New Zealand, as well as the top ten in 20 additional countries. It was the most played song of 2020 on adult contemporary radio in the US and was also the second-bestselling song in 2020 in the country. It is also certified Diamond in the US and Canada, 10× Platinum in Australia, and Gold or higher in 11 additional countries. It was also nominated for Record of the Year and Song of the Year at the 2021 Grammy Awards.