| Name | Source | Type |
|---|---|---|
| Q | Star Trek | |
| Qou'thalas | The Journeyman Project 3: Legacy of Time | |
| Quarians | Mass Effect | Humanoid, contained to environmental suits. Created the robotic Geth, who later rebelled against the Quarians. |
| Quarks | Doctor Who | |
| Quarren, aka "Squid Heads" | Star Wars | |
| Quintaglio | Robert J. Sawyer's books | |
| Quintesson | Transformers | |
| Qwardians | DC Comics |