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IFN1@
Identifiers
Aliases	IFNAinterferontype 1cluster
External IDs	GeneCards: ; OMA:- orthologs
Orthologs
	3438
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	n ; a
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	Wikidata
View/Edit Human

IFN1@

Last updated July 18, 2025

Interferon, type 1, cluster, also known as IFN1@, is a human gene.^[2]

References

↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: IFN1@ interferon, type 1, cluster".

Ferrantini M, Capone I, Belardelli F (2007). "Interferon-alpha and cancer: mechanisms of action and new perspectives of clinical use". Biochimie. 89 (6–7): 884–93. doi:10.1016/j.biochi.2007.04.006. PMID 17532550.
Nagata S, Mantei N, Weissmann C (1981). "The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha". Nature. 287 (5781): 401–8. doi:10.1038/287401a0. PMID 6159536. S2CID 29500779.
Radaeva S, Jaruga B, Kim WH, et al. (2004). "Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C". Biochem. J. 379 (Pt 1): 199–208. doi:10.1042/BJ20031495. PMC 1224051 . PMID 14690454.
Tecchio C, Huber V, Scapini P, et al. (2004). "IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells". Blood. 103 (10): 3837–44. doi: 10.1182/blood-2003-08-2806 . PMID 14726404. S2CID 22297033.
Wieczorek S, Dahmen N, Kasten M, et al. (2004). "A rare form of narcolepsy (HLA-DR2-) shows possible association with (functionally relevant) alpha-interferon gene polymorphisms". Psychiatr. Genet. 14 (1): 47–51. doi:10.1097/00041444-200403000-00008. PMID 15091316. S2CID 13012910.
Mihm S, Frese M, Meier V, et al. (2004). "Interferon type I gene expression in chronic hepatitis C". Lab. Invest. 84 (9): 1148–59. doi: 10.1038/labinvest.3700135 . PMID 15208644.
Palucka AK, Blanck JP, Bennett L, et al. (2005). "Cross-regulation of TNF and IFN-α in autoimmune diseases". Proc. Natl. Acad. Sci. U.S.A. 102 (9): 3372–7. Bibcode:2005PNAS..102.3372P. doi: 10.1073/pnas.0408506102 . PMC 552921 . PMID 15728381.
Zhao KW, Li D, Zhao Q, et al. (2006). "Interferon-alpha-induced expression of phospholipid scramblase 1 through STAT1 requires the sequential activation of protein kinase Cdelta and JNK". J. Biol. Chem. 280 (52): 42707–14. doi: 10.1074/jbc.M506178200 . PMID 16260419.
Civas A, Génin P, Morin P, et al. (2006). "Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon". J. Biol. Chem. 281 (8): 4856–66. doi: 10.1074/jbc.M506812200 . PMID 16380379.
Gómez-Benito M, Balsas P, Carvajal-Vergara X, et al. (2007). "Mechanism of apoptosis induced by IFN-alpha in human myeloma cells: role of Jak1 and Bim and potentiation by rapamycin". Cell. Signal. 19 (4): 844–54. doi:10.1016/j.cellsig.2006.10.009. PMID 17158029.
Rajeswari DN, Selvaraj P, Raghavan S, et al. (2007). "Influence of HLA-DR2 on perforin-positive cells in pulmonary tuberculosis". International Journal of Immunogenetics. 34 (5): 379–84. doi:10.1111/j.1744-313X.2007.00703.x. PMID 17845310. S2CID 31073749.
Karauzum SB, Yasar D, Dirice E, et al. (2007). "Lack of BCL-2 confers interferon-alpha sensitivity to B-cell lymphomas". Growth Factors. 25 (2): 94–100. doi:10.1080/08977190701345515. PMID 17852408. S2CID 30719569.

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[1] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-2] "Entrez Gene: IFN1@ interferon, type 1, cluster".

[1]

[2]

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IFN1@

References

Further reading