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Glutamate synthase (ferredoxin)

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glutamate synthase (ferredoxin)
Identifiers
EC no. 1.4.7.1
CAS no. 62213-56-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, glutamate synthase (ferredoxin) (EC 1.4.7.1) is an enzyme that catalyzes the chemical reaction

Contents

2
 
+ 2 oxidised
ferredoxin
 
 
 
2 H+
Glutamate synthase (ferredoxin)
 
2 H+
 
+
 
+ 2 reduced
ferredoxin
 

The two substrates of this enzyme are L-glutamic acid and oxidised ferredoxin. Its products are L-glutamine, α-ketoglutaric acid, reduced ferredoxin, and two protons. [1] [2] [3]

Classification

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with an iron-sulfur protein as acceptor.

Nomenclature

The systematic name of this enzyme class is L-glutamate:ferredoxin oxidoreductase (transaminating). Other names in common use include:

Biological role

This enzyme participates in nitrogen metabolism. It has 5 cofactors: flavin adenine dinucleotide, iron, sulfur, iron-sulfur, and flavoprotein.

See also

References

  1. Enzyme 1.4.7.1 at KEGG Pathway Database.
  2. Jang JE, Shaw K, Yu XJ, Petersen D, Pepper K, Lutzko C, Kohn DB (2006). "Specific and stable gene transfer to human embryonic stem cells using pseudotyped lentiviral vectors". Stem Cells Dev. 15 (1): 109–17. doi:10.1089/scd.2006.15.109. PMID   16522168.
  3. Lea PJ, Miflin BJ (1974). "Alternative route for nitrogen assimilation in higher plants". Nature. 251 (5476): 614–6. Bibcode:1974Natur.251..614L. doi:10.1038/251614a0. PMID   4423889. S2CID   4184284.


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