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Etoetonitazene

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Etoetonitazene
Etoetonitazene structure.png
Identifiers
  • 2-[2-[[4-(2-ethoxyethoxy)phenyl]methyl]-5-nitrobenzimidazol-1-yl]-N,N-diethylethanamine
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
Formula C24H32N4O4
Molar mass 440.544 g·mol−1
3D model (JSmol)
  • CCN(CC)CCN1C2=C(C=C(C=C2)[N+](=O)[O-])N=C1CC3=CC=C(C=C3)OCCOCC
  • InChI=1S/C24H32N4O4/c1-4-26(5-2)13-14-27-23-12-9-20(28(29)30)18-22(23)25-24(27)17-19-7-10-21(11-8-19)32-16-15-31-6-3/h7-12,18H,4-6,13-17H2,1-3H3
  • Key:NWEAJFXJKVCITM-UHFFFAOYSA-N

Etoetonitazene is a benzimidazole derivative with opioid effects, first developed in the 1950s as part of the research that led to better-known compounds such as etonitazene. It is an analogue of etonitazene where the ethoxy sidechain has been extended to ethoxyethoxy. It is less potent than other benzimidazole class opioids, but is still a potent mu opioid receptor agonist with around 50x the potency of morphine, and has been sold as a designer drug since around 2022. [1] [2]

See also

References

  1. ↑ "A review of the evidence on the use and harms of 2-benzyl benzimidazole ('nitazene') and piperidine benzimidazolone ('brorphine-like') opioids" (PDF). UK: Advisory Council on the Misuse of Drugs. July 2022.
  2. ↑ Hasegawa K, Minakata K, Suzuki M, Suzuki O (July 2022). "Non-fentanyl-derived synthetic opioids emerging during recent years". Forensic Toxicology. 40 (2): 234–243. doi: 10.1007/s11419-022-00624-y . PMC   9052731 . PMID   36454418.



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