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Encephaloduroarteriosynangiosis

Last updated February 05, 2026

Encephaloduroarteriosynangiosis, or encephalo-duro-arterio-synangiosis^[1] (abbreviated EDAS, encephalo-, of the brain; duro- , hard; arterio- , of the artery; synangial, relating to the synangium) is a neurosurgical procedure performed to treat moyamoya syndrome.^[2]^[3]^[4]

References

↑ Matsushima, T.; Fukui, M.; Kitamura, K.; Hasuo, K.; Kuwabara, Y.; Kurokawa, T. (1990). "Encephalo-duro-arterio-synangiosis in children with moyamoya disease". Acta Neurochirurgica. 104 (3–4): 96–102. doi:10.1007/BF01842826. ISSN 0001-6268. PMID 2251949.
↑ Gonzalez, Nestor R.; Dusick, Joshua R.; Connolly, Mark; Bounni, Firas; Martin, Neil A.; Van de Wiele, Barbara; Liebeskind, David S.; Saver, Jeffrey L. (2015). "Encephaloduroarteriosynangiosis for adult intracranial arterial steno-occlusive disease: long-term single-center experience with 107 operations". Journal of Neurosurgery. 123 (3): 654–661. doi: 10.3171/2014.10.JNS141426 . PMID 26067617. [EDAS] is a form of revascularization that has shown promising early results in the treatment of adult patients with moyamoya disease [and, more recently,] in patients with intracranial atherosclerotic steno-occlusive disease (ICASD).
↑ "Encephaloduroarteriosynangiosis (EDAS)". Columbia Neurosurgery in New York City. 8 April 2021. Retrieved 4 February 2026. EDAS reroutes a section of an artery that is normally connected to the scalp onto the surface of the brain. New blood vessels grow from this artery into the brain itself. The goal [is] to provide a new source of blood for an ischemic area of the brain. [It] is performed to treat a condition of progressively restricted blood flow to the brain known as moyamoya. [It belongs to a group of] procedures termed indirect revascularization procedures [,] in which the brain grows vessels from a new blood supply. [This group of procedures are] performed most often in children [and can be performed on adults, though they] are more commonly treated with a form of direct revascularization called EC-IC bypass.
↑ Ross, Ian B.; Shevell, Michael I.; Montes, Jose L.; Rosenblatt, Bernard; Watters, Gordon V.; Farmer, Jean-Pierre; O'Gorman, Augustin M. (1994-05-01). "Encephaloduroarteriosynangiosis (EDAS) for the treatment of childhood moyamoya disease". Pediatric Neurology. 10 (3): 199–204. doi:10.1016/0887-8994(94)90023-X. ISSN 0887-8994. [EDAS] involves the transposition of a segment of a scalp artery onto the surface of the [brain. Such surgical] treatment [is] aimed at improving collateral blood flow.

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[1] Matsushima, T.; Fukui, M.; Kitamura, K.; Hasuo, K.; Kuwabara, Y.; Kurokawa, T. (1990). "Encephalo-duro-arterio-synangiosis in children with moyamoya disease". Acta Neurochirurgica. 104 (3–4): 96–102. doi:10.1007/BF01842826. ISSN 0001-6268. PMID 2251949.

[2] Gonzalez, Nestor R.; Dusick, Joshua R.; Connolly, Mark; Bounni, Firas; Martin, Neil A.; Van de Wiele, Barbara; Liebeskind, David S.; Saver, Jeffrey L. (2015). "Encephaloduroarteriosynangiosis for adult intracranial arterial steno-occlusive disease: long-term single-center experience with 107 operations". Journal of Neurosurgery. 123 (3): 654–661. doi: 10.3171/2014.10.JNS141426 . PMID 26067617. [EDAS] is a form of revascularization that has shown promising early results in the treatment of adult patients with moyamoya disease [and, more recently,] in patients with intracranial atherosclerotic steno-occlusive disease (ICASD).

[3] "Encephaloduroarteriosynangiosis (EDAS)". Columbia Neurosurgery in New York City. 8 April 2021. Retrieved 4 February 2026. EDAS reroutes a section of an artery that is normally connected to the scalp onto the surface of the brain. New blood vessels grow from this artery into the brain itself. The goal [is] to provide a new source of blood for an ischemic area of the brain. [It] is performed to treat a condition of progressively restricted blood flow to the brain known as moyamoya. [It belongs to a group of] procedures termed indirect revascularization procedures [,] in which the brain grows vessels from a new blood supply. [This group of procedures are] performed most often in children [and can be performed on adults, though they] are more commonly treated with a form of direct revascularization called EC-IC bypass.

[4] Ross, Ian B.; Shevell, Michael I.; Montes, Jose L.; Rosenblatt, Bernard; Watters, Gordon V.; Farmer, Jean-Pierre; O'Gorman, Augustin M. (1994-05-01). "Encephaloduroarteriosynangiosis (EDAS) for the treatment of childhood moyamoya disease". Pediatric Neurology. 10 (3): 199–204. doi:10.1016/0887-8994(94)90023-X. ISSN 0887-8994. [EDAS] involves the transposition of a segment of a scalp artery onto the surface of the [brain. Such surgical] treatment [is] aimed at improving collateral blood flow.

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