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Dichloromethane dehalogenase

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Dichloromethane dehalogenase
Identifiers
EC no. 4.5.1.3
CAS no. 97002-70-5
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IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
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NCBI proteins

Dichloromethane dehalogenase (EC 4.5.1.3; systematic name dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming)) is a lyase enzyme that generates formaldehyde. [1]

dichloromethane + H2O = formaldehyde + 2 chloride

Glutathione is required for its activity.

References

  1. Kohler-Staub D, Leisinger T (May 1985). "Dichloromethane dehalogenase of Hyphomicrobium sp. strain DM2". Journal of Bacteriology. 162 (2): 676–81. doi:10.1128/jb.162.2.676-681.1985. PMC   218903 . PMID   3988708.


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