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Dibenzothiophene dihydrodiol dehydrogenase

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dibenzothiophene dihydrodiol dehydrogenase
Identifiers
EC no. 1.3.1.60
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, dibenzothiophene dihydrodiol dehydrogenase (EC 1.3.1.60) is an enzyme that catalyzes the chemical reaction

+ NAD+
 
 
 
H+
Dibenzothiophene dihydrodiol dehydrogenase
 
H+
 
+ NADH
 

The two substrates of this enzyme are cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 1,2-dihydroxydibenzothiophene, reduced NADH, and a proton. [1] [2] [3]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase.

References

  1. Enzyme 1.3.1.60 at KEGG Pathway Database.
  2. Laborde AL, Gibson DT (1977). "Metabolism of dibenzothiophene by a Beijerinckia species". Appl. Environ. Microbiol. 34 (6): 783–90. Bibcode:1977ApEnM..34..783L. doi:10.1128/aem.34.6.783-790.1977. PMC   242748 . PMID   596875.
  3. Denome SA, Stanley DC, Olson ES, Young KD (1993). "Metabolism of dibenzothiophene and naphthalene in Pseudomonas strains: complete DNA sequence of an upper naphthalene catabolic pathway". J. Bacteriol. 175 (21): 6890–901. doi:10.1128/jb.175.21.6890-6901.1993. PMC   206814 . PMID   8226631.


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