| diaminopimelate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.4.1.16 | ||||||||
| CAS no. | 60894-21-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, diaminopimelate dehydrogenase (EC 1.4.1.16) is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are meso-diaminopimeilic acid, water, and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are (S)-2-amino-6-oxopimelic acid, ammonia, reduced NADPH, and a proton. [1] [2] [3]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating). Other names in common use include meso-alpha,epsilon-diaminopimelate dehydrogenase, and meso-diaminopimelate dehydrogenase. This enzyme participates in lysine biosynthesis.
