| Portrait | Name (Birth–Death) | Office term | Cabinet |
|---|
| Valeriu Cebotari (born 1955) | 27 August 1991 | 1 July 1992 | Muravschi |
| Gheorghe Efros (born 1948) |
 | Constantin Tampiza (born 1947) Minister of Economy and Finance |
 | Mihai Coșcodan (1940–2016) | 4 August 1992 | 5 April 1994 | Sangheli I |
| Nicolae Oleinic (1943–2019) |
| Valentin Cunev (1946–2023) | 4 August 1992 | 24 January 1997 | Sangheli I–II |
| Grigore Ojog (born 1954) | 16 September 1994 | 24 January 1997 | Sangheli II |
| Valeriu Bulgari (born 1956) | 5 April 1994 | 17 June 1996 | Sangheli I |
| 24 January 1997 | 22 May 1998 | Sangheli II Ciubuc I |
| Ion Guțu (born 1943) Minister of Economy and Reforms | 5 April 1994 | 22 May 1998 | Sangheli II Ciubuc I |
 | Ion Sturza (born 1960) Minister of Economy and Reforms | 22 May 1998 | 12 March 1999 | Ciubuc II |
 | Valentin Dolganiuc (born 1957) Deputy PM for Industrial Policy |
 | Nicolae Andronic (born 1959) Deputy PM for Judicial Affairs |
| Oleg Stratulat (born 1957) Deputy PM for Social Policy and Science | 22 May 1998 | 21 December 1999 | Ciubuc II Sturza |
 | Alexandru Muravschi (born 1950) Minister of Economy and Reforms | 12 March 1999 | 21 December 1999 | Sturza |
 | Valeriu Cosarciuc (born 1955) | 21 December 1999 | 19 April 2001 | Braghiș |
| Lidia Guțu (born 1954) |
| Eugeniu Șlopac (born 1951) Minister of Economy and Reforms | 21 December 1999 | 6 March 2000 |
| Andrei Cucu (born 1948) Minister of Economy | 6 March 2000 | 4 February 2002 | Braghiș Tarlev I |
| Ștefan Odagiu (born 1965) Minister of Economy | 14 May 2002 | 2 July 2003 | Tarlev I |
| Dmitri Todoroglo (born 1944) Minister of Agriculture and Food Industry | 19 April 2001 | 19 April 2005 |
| Valerian Cristea (born 1950) | 19 April 2001 | 15 November 2006 | Tarlev I–II |
| Andrei Stratan (born 1966) Minister of Foreign Affairs | 21 December 2004 | 25 September 2009 | Tarlev I–II Greceanîi I–II |
 | Vitalie Vrabie (born 1964) | 15 November 2006 | 16 July 2007 | Tarlev II |
 | Victor Stepaniuc (born 1958) | 16 January 2008 | 11 September 2009 | Tarlev II Greceanîi I–II |
| Valentin Mejinschi (born 1967) Deputy PM for Issues of Corruption, Migration and Human Trafficking | 21 October 2008 | 10 June 2009 | Greceanîi I |
 | Iurie Roșca (born 1961) | 10 June 2009 | 25 September 2009 | Greceanîi II |
 | Ion Negrei (born 1958) Deputy PM for Social Affairs | 25 September 2009 | 14 January 2011 | Filat I |
 | Victor Osipov (born 1971) Deputy PM for Reintegration | 25 September 2009 | 14 January 2011 |
| 18 February 2015 | 20 January 2016 | Gaburici Streleț |
 | Iurie Leancă (born 1963) Minister of Foreign Affairs and European Integration; Deputy PM for European Integration | 25 September 2009 | 31 May 2013 | Filat I–II |
| 10 January 2018 | 8 June 2019 | Filip |
 | Valeriu Lazăr (born 1968) Minister of Economy | 25 September 2009 | 2 July 2014 | Filat I–II Leancă |
| Mihai Moldovanu (born 1965) Deputy PM for Social Affairs | 14 January 2011 | 31 May 2013 | Filat II |
 | Eugen Carpov (born 1966) Deputy PM for Reintegration | 14 January 2011 | 18 February 2015 | Filat II Leancă |
| Tatiana Potîng (born 1971) Deputy PM for Social Affairs | 31 May 2013 | 18 February 2015 | Leancă |
 | Andrian Candu (born 1975) Minister of Economy | 3 July 2014 | 23 January 2015 |
 | Natalia Gherman (born 1969) Minister of Foreign Affairs and European Integration | 31 May 2013 | 20 January 2016 | Leancă Gaburici Streleț |
 | Stéphane Christophe Bridé (born 1971) Minister of Economy | 18 February 2015 | 20 January 2016 | Gaburici Streleț |
 | Gheorghe Brega (born 1951) Deputy PM for Social Affairs | 30 July 2015 | 30 May 2017 | Streleț Filip |
 | Gheorghe Bălan (born 1975) Deputy PM for Reintegration | 20 January 2016 | 21 December 2017 | Filip |
 | Cristina Lesnic (born 1982) Deputy PM for Reintegration | 10 January 2018 | 8 June 2019 |
| 16 March 2020 | 9 November 2020 | Chicu |
 | Octavian Calmîc (born 1974) Minister of Economy | 20 January 2016 | 21 December 2017 | Filip |
 | Andrei Galbur (born 1975) Minister of Foreign Affairs and European Integration |
 | Andrei Năstase (born 1975) Minister of Internal Affairs | 8 June 2019 | 14 November 2019 | Sandu |
 | Vasilii Șova (born 1959) Deputy PM for Reintegration |
 | Alexandru Flenchea (born 1979) Deputy PM for Reintegration | 14 November 2019 | 16 March 2020 | Chicu |
 | Sergiu Pușcuța (born 1972) Minister of Finance | 14 November 2019 | 31 December 2020 |
 | Olga Cebotari (born 1992) Deputy PM for Reintegration | 9 November 2020 | 6 August 2021 |
 | Vladislav Kulminski (born 1972) Deputy PM for Reintegration | 6 August 2021 | 5 November 2021 | Gavrilița |
 | Andrei Spînu (born 1986) Minister of Infrastructure and Regional Development | 6 August 2021 | 16 February 2023 |
 | Iurie Țurcanu (born 1973) Deputy PM for Digitalization |
 | Nicu Popescu (born 1981) Minister of Foreign Affairs and European Integration | 6 August 2021 | 26 January 2024 | Gavrilița Recean |
 | Oleg Serebrian (born 1969) Deputy PM for Reintegration | 19 January 2022 | 30 June 2025 |
 | Roman Roșca (born 1982) Deputy PM for Reintegration | 23 July 2025 | 1 November 2025 | Recean |
 | Dumitru Alaiba (born 1982) Minister of Economic Development and Digitalization | 16 February 2023 | 14 March 2025 |
 | Doina Nistor (born 1977) Minister of Economic Development and Digitalization | 14 March 2025 | 1 November 2025 |
 | Vladimir Bolea (born 1971) Minister of Agriculture and Food Industry; Minister of Infrastructure and Regional Development | 16 February 2023 | Incumbent | Recean Munteanu |
 | Mihai Popșoi (born 1987) Minister of Foreign Affairs | 29 January 2024 | Incumbent |
 | Cristina Gherasimov (born 1984) Deputy PM for European Integration | 5 February 2024 | Incumbent |
 | Valeriu Chiveri (born 1963) Deputy PM for Reintegration | 1 November 2025 | Incumbent | Munteanu |
 | Eugen Osmochescu (born 1972) Minister of Economic Development and Digitalization |
Moldovaportal 
