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Cis-dihydroethylcatechol dehydrogenase

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cis-dihydroethylcatechol dehydrogenase
Identifiers
EC no. 1.3.1.66
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, cis-dihydroethylcatechol dehydrogenase (EC 1.3.1.66) is an enzyme that catalyzes the chemical reaction

+ NAD+
 
 
 
H+
Cis-dihydroethylcatechol dehydrogenase
 
H+
 
+ NADH
 

The two substrates of this enzyme are cis-1,2-dihydro-3-ethylcatechol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 3-ethylcatechol, reduced NADH, and a proton. [1] [2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase. This enzyme participates in ethylbenzene degradation.

References

  1. Enzyme 1.3.1.66 at KEGG Pathway Database.
  2. Gibson DT, Gschwendt B, Yeh WK, Kobal VM (1973). "Initial reactions in the oxidation of ethylbenzene by Pseudomonas putida". Biochemistry. 12 (8): 1520–8. doi:10.1021/bi00732a008. PMID   4699984.


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