英文互译镜像站

Brown induration

Last updated
Lung with brown induration in the lower lobe, nodular lesions beneath thickened pleura, congested capillaries with erythrocyte extravasation, hemosiderin-laden macrophages, and pulmonary artery intimal hyperplasia. Brown induration.jpg
Lung with brown induration in the lower lobe, nodular lesions beneath thickened pleura, congested capillaries with erythrocyte extravasation, hemosiderin-laden macrophages, and pulmonary artery intimal hyperplasia.

Brown induration is fibrosis and hemosiderin pigmentation of the lungs due to long standing pulmonary congestion (chronic passive congestion). Occurs with mitral stenosis and left sided heart failure.

Pathology

The lung vessels are congested with blood and this leads to pulmonary edema when plasma escapes in alveolar spaces. Rupture of congested capillaries leads to release of hemosiderin from damaged red blood cells. When alveolar macrophages engulf hemosiderin they are called heart failure cells. Death of heart failure cells in their journey back to lung tissue with subsequent hemosiderin release leads to lung fibrosis. [1] [2] [3]

References

  1. ↑ Stedman's Medical Dictionary for the Health Professions and Nursing
  2. ↑ Pathology 3rd edition, BRS series, Schneider et al
  3. ↑ Idiopathic pulmonary haemosiderosis (essential brown induration of the lung), Wyllie, W.G et al
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.
镜像小偷 整站镜像下载 镜像小偷 超级站群助手 站点克隆软件