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Beta-Ala-His dipeptidase

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Beta-Ala-His dipeptidase
Identifiers
EC no. 3.4.13.20
CAS no. 525589-43-9
Databases
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BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
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NCBI proteins

Beta-Ala-His dipeptidase (EC 3.4.13.20, serum carnosinase) is an enzyme. [1] [2] This enzyme catalyses the following chemical reaction

Preferential hydrolysis of the beta-Ala!His dipeptide (carnosine), and also anserine, Xaa!His dipeptides and other dipeptides including homocarnosine

This enzyme is present in the serum of humans and higher primates.

References

  1. Lenney JF, George RP, Weiss AM, Kucera CM, Chan PW, Rinzler GS (August 1982). "Human serum carnosinase: characterization, distinction from cellular carnosinase, and activation by cadmium". Clinica Chimica Acta; International Journal of Clinical Chemistry. 123 (3): 221–31. doi:10.1016/0009-8981(82)90166-8. PMID   7116644.
  2. Jackson MC, Kucera CM, Lenney JF (February 1991). "Purification and properties of human serum carnosinase". Clinica Chimica Acta; International Journal of Clinical Chemistry. 196 (2–3): 193–205. doi:10.1016/0009-8981(91)90073-L. PMID   1903095.
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