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Ananain

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Ananain
Identifiers
EC no. 3.4.22.31
CAS no. 119129-70-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
PubMed articles
NCBI proteins

Ananain (EC 3.4.22.31, stem bromelain , fruit bromelain) is an enzyme. [1] [2] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with broad specificity for peptide bonds. Best reported small molecule substrate Bz-Phe-Val-Arg-NHMec

This enzyme is isolated from stem of pineapple plant, Ananas comosus .

References

  1. Rowan AD, Buttle DJ, Barrett AJ (November 1988). "Ananain: a novel cysteine proteinase found in pineapple stem". Archives of Biochemistry and Biophysics. 267 (1): 262–70. doi:10.1016/0003-9861(88)90031-8. PMID   3196029.
  2. Rowan AD, Buttle DJ, Barrett AJ (March 1990). "The cysteine proteinases of the pineapple plant". The Biochemical Journal. 266 (3): 869–75. PMC   1131219 . PMID   2327970.
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