英文互译镜像站

5,7-Dichlorokynurenic acid

Last updated
5,7-Dichlorokynurenic acid
DCKA.svg
Names
Preferred IUPAC name
5,7-Dichloro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
UNII
  • InChI=1S/C10H5Cl2NO3/c11-4-1-5(12)9-6(2-4)13-7(10(15)16)3-8(9)14/h1-3H,(H,13,14)(H,15,16) X mark.svgN
    Key: BGKFPRIGXAVYNX-UHFFFAOYSA-N X mark.svgN
  • InChI=1/C10H5Cl2NO3/c11-4-1-5(12)9-6(2-4)13-7(10(15)16)3-8(9)14/h1-3H,(H,13,14)(H,15,16)
    Key: BGKFPRIGXAVYNX-UHFFFAOYAD
  • C1=C(C=C2C(=C1Cl)C(=O)C=C(N2)C(=O)O)Cl
Properties
C10H5Cl2NO3
Molar mass 258.05 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
X mark.svgN  verify  (what is  Yes check.svgYX mark.svgN ?)

5,7-Dichlorokynurenic acid (DCKA) is a selective NMDA receptor antagonist acting at the glycine site of the NMDA receptor complex. [1]

See also

References

  1. ↑ McNamara, D; Smith, EC; Calligaro, DO; O'Malley, PJ; McQuaid, LA; Dingledine, R (November 1990). "5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors". Neuroscience Letters. 120: 17–20. PMID   2149877.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.
MirrorElf 蜘蛛池+镜像 泛域名镜像 伪原创镜像站 英文互译镜像站