| 2026 Challenger de Santiago | |
|---|---|
| Date | 9–15 March |
| Edition | 20th |
| Surface | Clay |
| Location | Santiago, Chile |
| 2025 Champions | |
| Singles | |
 Daniel Elahi Galán | |
| Doubles | |
 Vasil Kirkov /  Matías Soto | |
The 2026 Challenger de Santiago was a professional tennis tournament played on clay courts. It was the 20th edition of the tournament which was part of the 2026 ATP Challenger Tour. It took place in Santiago, Chile between 9 and 15 March 2026.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 PAR | Daniel Vallejo | 104 | 1 |
 NED | Guy den Ouden | 156 | 2 |
 POR | Jaime Faria | 163 | 3 |
| POR | Henrique Rocha | 169 | 4 |
 ARG | Alex Barrena | 179 | 5 |
| COL | Daniel Elahi Galán | 182 | 6 |
| ARG | Juan Pablo Ficovich | 186 | 7 |
 BRA | João Lucas Reis da Silva | 205 | 8 |
The following players received wildcards into the singles main draw:
Diego Dedura Bastián Malla Amador SalazarThe following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
vs. / vs. /