Western Reserve may refer to:

• The Connecticut Western Reserve, now northeastern Ohio, U.S.
• Western Reserve Academy, Hudson, Ohio, founded 1826
• Western Reserve Eclectic Institute, now Hiram College, Hiram, Ohio, founded 1850
• Western Reserve Historical Society
• Western Reserve High School (Berlin Center, Ohio)
• Western Reserve High School (Collins, Ohio)
• Western Reserve Public Media and Western Reserve PBS, branding of public television stations WEAO-TV and WNEO-TV
• Western Reserve Land Conservancy, a nonprofit land trust in Northeast Ohio
• Case Western Reserve University, Cleveland, Ohio. Founded in 1826 as Western Reserve College and later named Western Reserve University; merged with Case Institute of Technology in 1967
• SS Western Reserve , a steel-plate freighter that sank in Lake Superior in 1892
• Western Reserve Hospital, a local hospital in Cuyahoga Falls, Ohio, founded 1943.
• The Manitoba West Reserve or Western Reserve in South Central Manitoba, Canada, immediately north of the American border, that was settled by Russian Mennonites beginning in 1875

This disambiguation page lists articles associated with the title Western Reserve.
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