Van Sant or van 't Sant or van't Sant is a surname, and may refer to:

• François van 't Sant (1883–1966), Dutch head-commissioner of police
• Gus Van Sant (born 1952), American film director and musician
• John Van Sant (1915–1972), American politician from Pennsylvania
• Joshua Van Sant (1803–1884), U.S. Representative and Mayor of Baltimore (1871–1875)
• Mike Van Sant, American drag racer
• Onno Hattinga van't Sant (born 3 May 1946), Dutch diplomat
• Peter Van Sant (born 1953), American reporter
• Samuel Rinnah Van Sant (1844–1936), Governor of Minnesota (1901–1905)
• Tom Van Sant (1931–2023), American artist

See also

• Sant (surname)

Surname list

This page lists people with the surname Van Sant.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.