Look up UCSC in Wiktionary, the free dictionary.

UCSC is the University of California, Santa Cruz, a public research university in Santa Cruz, California, United States.

UCSC may also refer to:

• Università Cattolica del Sacro Cuore, a private Catholic university based in Milan, Italy
• University of Colombo School of Computing, a college affiliated with the University of Colombo in Sri Lanka
• University City Science Center, an urban research park in Philadelphia, Pennsylvania, United States
• Universidad Católica de la Santísima Concepción, a private catholic university in Chile

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