3x3 or three by three may refer to:
- 3×3 , a 1982 extended play by Genesis
- 3x3 (EP), a 2023 extended play by Odetari and 9lives
- "3 x 3", a 2023 song by Pylon Reenactment Society
- 3 by 3 (Inside No. 9), an episode of the British anthology comedy series Inside No. 9.
- 3x3, the classic version of the Rubik's Cube
- 3x3 basketball, a variation of basketball played three-a-side
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