Literature

• T, a novel by Victor Pelevin
• T (magazine), a fashion magazine, full name T: The New York Times Style Magazine
• "T" Is for Trespass , the twentieth novel in Sue Grafton's "Alphabet mystery" series, published in 2007
• T-unit, a grammatical term

Film and television

• Big T, ring name of American retired professional wrestler Ahmed Johnson (born 1963)
• Mr. T (born 1952), American television actor
• T, the production code for the 1965 Doctor Who serial Galaxy 4
• The T logo for the American Spanish-language network Telemundo
• T (2023 film), an Indian Odia-language film by Jitesh Kumar Parida

Music

• Ice-T (born 1958), American rapper and actor
• T (Funker Vogt album), a 2000 aggrotech album by Funker Vogt
• T (TVXQ album), a 2008 TVXQ album
• T (Teflon Brothers album), a 2009 album by Finnish hip hop group Teflon Brothers
• "t," an Iamamiwhoami song
• T, abbreviation for tutti
• T, abbreviation for tenor
• t, note abbreviation in tonic sol-fa for seventh scale degree
• T-Babe, a virtual pop singer

Video games

• T (teen), a game rating from the Entertainment Software Rating Board which the board believes is suitable for those aged 13 years and older

Biology and medicine

• Troponin T, one of the three troponins
• Haplogroup T (mtDNA), a human mitochondrial DNA (mtDNA) haplogroup
• T cells, part of the components of the immune system along with B cells
• T, the one-letter code used for threonine, one of the 20 amino acids used in transcription of a polypeptide chain
• Thymine, one of the four nucleic acids of DNA
• T, gene and protein symbol for the transcription factor brachyury
• Thoracic vertebrae T-1 through T-12
• T wave, the repolarization wave of cardiac ventricles in electrocardiography
• T, a common abbreviation for the male sex hormone testosterone

Palaeontology

• T-rex, abbreviation for Tyrannosaurus rex

Meteorology

• Thunderstorm
• T-number in the Dvorak technique, a way to rate storm intensity

Physics and chemistry

• T, symbol for tritium, a radioactive isotope of hydrogen
• T-symmetry in particle physics
• Class T, a cool brown dwarf class of stars
• ΔT (disambiguation): a variety of meanings related to changes in a quantity denoted by T, such as time or temperature

Mathematics

• T score, a statistical term
• Student's t-distribution, statistical term
• T, in modal logic
• ${\displaystyle \mathbb {T} ^{n}}$, the n-dimensional torus (${\displaystyle \mathbb {R} ^{n}/\mathbb {Z} ^{n}}$)
• ${\displaystyle \mathbb {T} }$, the Circle group
• A^T, the transpose of a matrix A

Equipment

• Ford Model T, a motor car produced in the U.S. 1908–1927
• NZR T class steam locomotives in New Zealand
• OS T1000, an Oslo Metro train
• T gauge, a scale for model railroad trains
• Tank locomotive

Public transport