Saffron is a spice.
Saffron may also refer to:
- Saffron (trade), the business of producing and selling saffron
- Saffron (color), a shade of orange-yellow
- Saffron (album), a 2010 album by Ron Contour and Factor
- Saffron (singer) (born 1968), lead singer of Republica
- Saffron Brand Consultants, a design firm and consultant
- Saffron Type System, a font-rendering technology used in Adobe Flash
- Saffron (Ranma ½), a character in Ranma ½
- Saffron Monsoon, a character in Absolutely Fabulous
- Saffron, a minor character in the Firefly universe
- Saffron, a character in the video game Super Paper Mario
- "Saffron", a song by the Smashing Pumpkins from Atum: A Rock Opera in Three Acts , 2023
- Saffron Bee, a member of the Chaotix in the Archie Sonic the Hedgehog comics
- Saffron City, one of the largest settlements of the Kanto region in Pokémon games
