A power of two is a number of the form 2ⁿ, meaning 2 multiplied by itself n times.

Power of two or variations may also refer to:

• The Power of Two , a 2009 album by Michael Feinstein and Cheyenne Jackson
• "Power of Two" (song), a song by the Indigo Girls
• Power of 2 (book), a self-help book about partnerships by Rodd Wagner and Gale Muller
• "The Power of Two" (Charmed episode), an episode of the television series Charmed
• The Power of Two, the first book in the novel series Twitches by H. B. Gilmour and Randi Reisfeld
• Epic Mickey 2: The Power of Two , a 2012 video game produced by Junction Point Studios
• Max & Paddy's The Power of Two, a DVD release from the television show Max and Paddy's Road to Nowhere
• "Power of Two", a song from the television series The Acolyte
• Battle for Dream Island: The Power of Two , the fifth season of the animated web series Battle for Dream Island

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