Mosca is an Italian surname. Notable people with the surname include:

• Alessia Mosca (born 1975), Italian politician
• Angelo Mosca (1937–2021), Canadian Football League player and professional wrestler
• Antonio Mosca (1870–1951), Italian painter
• Bianca Mosca (dead 1950), London-based fashion designer
• Claudio Mosca (born 1991), Argentine footballer
• Enrique Mosca (1880-1950), Argentine lawyer and politician
• Frank Mosca (born 1976), American film producer
• Gaetano Mosca (1858–1941), Italian political scientist, journalist, and public servant
• Giuseppe Mosca (1772–1839), Italian opera composer
• Jacopo Mosca (born 1993), Italian cyclist
• John Mosca (restaurateur) (1922–2011), American restauranteur, founder of Mosca's
• John Mosca (musician) (born 1950), American jazz trombonist
• Lino Mosca (1907−1992), Italian professional football player
• Luigi Mosca (1775–1824), Italian composer of operas and sacred music, and singing teacher
• Maurizio Mosca (1940–2010), Italian sports journalist and television presenter
• Michele Mosca, Italian physics researcher and professor of mathematics
• Paolo Mosca (1943–2014), Italian journalist, writer, singer, and television presenter
• Pierre Mosca (born 1949), Italian-born French former footballer and coach
• Rafael Mosca (born 1982), Brazilian swimmer
• Rich Mosca (born c. 1948), former American football player and coach
• Sal Mosca (1927–2007), American jazz pianist
• Simone Mosca (1492–1554), Italian sculptor
• Stefania Mosca (1957–2009), Venezuelan writer
• Tommaso Mosca (born 2000), Italian racing driver

Fictional characters

• Mosca, of Ben Jonson's 1606 play Volpone
• Mosca, of The Godfather Part III
• Frank Mosca, of Miami Vice
• Gola Mosca, of Reborn! manga and anime series
• Walter Mosca, of Mario Puzo's novel The Dark Arena

Surname list

This page lists people with the surname Mosca.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.