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A molybdenum cofactor is a biochemical cofactor that contains molybdenum.^{[ citation needed ]}

Examples include:

• Molybdopterin the organophosphate-dithiolate ligand that binds molybdenum and tungsten in most molybdenum- (except nitrogenases) and all tungsten-containing proteins.
• FeMoco, a metal cluster that contains Fe, Mo, and S that is found in some nitrogenases

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