McGuffin is a surname of Irish origin, thought to originate from County Donegal. It is an Anglicized form of the Gaelic Mag Dhuibhfinn. Notable people with the surname include:
- Meg McGuffin (born c. 1990), American beauty-pageant titleholder
- David McGuffin (fl. 2000s), Canadian television correspondent
- Gary and Joanie McGuffin (born 1959, born 1960), Canadian explorers, authors, and conservation photographer
- Peter McGuffin (1949–2024), Northern Irish geneticist
- Samuel McGuffin (1863–1952), Northern Ireland politician
- Tyson McGuffin (born 1989), American professional pickleball player
This page lists people with the surname McGuffin.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.