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Margaret of Hohenzollern-Nuremberg (1367-1406) was a daughter of Burgrave Frederick V of Nuremberg and his wife, Elisabeth of Meissen.

In 1383 in Kulmbach, she married Landgrave Herman II of Hesse, as his second wife. They had the following children:

• Anna (1385–1386)
• Henry (1387–1394)
• Elisabeth (1388–1394)
• Margarete ( 1389–1446), married to Henry I of Brunswick-Lüneburg
• Agnes (1391–1471), married to Otto II of Brunswick-Göttingen
• Hermann (1396–1406)
• Frederick (1398–1402)
• Louis (1402–1458), succeeded as Landgrave of Hesse

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