The following is a list of notable people from Latakia and ancient Laodicea.

Ancient

• Anatolius of Laodicea
• Apollinaris of Laodicea
• Eusebius of Laodicea
• Philonides of Laodicea
• Themison of Laodicea

Modern

• Hafez al-Assad, former president of Syria
• Bashar al-Assad, former president of Syria
• Adunis, poet
• A. R. Frank Wazzan, professor of engineering; Dean Emeritus, of the UCLA Samueli School of Engineering, UCLA
• Hasan Alkhayer, poet and politician
• Yusuf Yasin, an advisor to King Abdulaziz
• Hanna Mina, novelist
• Izz ad-Din al-Qassam, sheikh and a rebel leader in Palestine
• Michel Kilo, writer and activist
• Aref Dalila, economist and activist
• Badawi al-Jabal, poet
• Mustafa Hamsho, professional boxer
• Zaki al-Arsuzi, politician and founder of Baath Party
• Maram al-Masri, poet
• Yusuf Yasin, politician and journalist
• Adnan Alkateb, editorial Manager of Hia Magazine.
• Khalida Said, writer
• Rasha Abbas, author and journalist