Arts and entertainment

• Larry D. Alexander, American artist/writer
• Larry Boone, American country singer
• Larry Collins, American musician, member of the rockabilly sibling duo The Collins Kids
• Larry Carlton (born 1948), American jazz guitarist and singer
• Larry Csonka, American wrestling journalist
• Larry David (born 1947), Emmy-winning American actor, writer, comedian, producer and film director
• Larry Emdur, Australian television personality
• Larry Feign, American cartoonist working in Hong Kong
• Larry Ferrari (1932-1997), American organist
• Larry Fine (1902–1975), American comedian and actor, one of the Three Stooges
• Larry Gates, American actor
• Larry Gatlin, American country singer
• Larry Gayao (better known as Larry g(EE)), Filipino-American soul-pop artist
• Larry Gelbart (1928–2009), American screenwriter, playwright, director and author
• Larry Graham, founder of American funk band Graham Central Station
• Larry Hagman, American actor, best known for the TV series I Dream of Jeannie and Dallas
• Larry Heath, Australian entrepreneur and publisher, founder of the National Live Music Awards
• Larry Henley (1937–2014), American singer and songwriter, member of The Newbeats
• Larry Hovis, American actor and singer
• Larry Joyner (born 1964), American football player
• Larry June, American rapper
• Larry Junstrom (1949–2019), American bassist, founding member of the rock band Lynyrd Skynyrd
• Larry Kenney, American radio DJ and voice actor on Imus in the Morning
• Larry King (1933–2021), American talk show host of Larry King Live on CNN
• Larry Knechtel (1940–2009), American keyboardist and bassist
• Larry Lavender, American dancer and scholar
• Larry Lujack (1940–2013), American radio disc jockey
• Larry Mathews (born 1955), American actor
• Larry Mathews (musician), Irish musician
• Larry McMurtry, American novelist
• Larry Miller, an American guitarist from Ann Arbor, Michigan
• Larry Mullen Jr., Irish drummer and founder of the group U2
• Larry Niven, American science fiction author
• Larry Page (singer) (1936–2024), English pop singer and record producer
• Larry Poole, American actor and film producer
• Larry Ramos (1942–2014), American musician, member of the band the Association
• Larry Sanders (born 1954), American singer aka L.V.
• Larry Santos (born 1941), American pop music singer-songwriter
• Larry Shay (1897–1988), American songwriter
• Larry Storch (1923–2022), American actor and comedian, best known for his TV work in F Troop
• Larry Taylor (1942–2019), American bassist, member of the rock band Canned Heat
• Larry Verne (1936–2013), American singer
• Larry Wallis (1949–2019), English rock guitarist and songwriter, early member of the rock band Motörhead
• Larry Walters (1949–1993) American truck driver, also known as Lawn Chair Larry
• Larry Wilmore, American political satirist, and host of The Nightly Show with Larry Wilmore
• Larry the Cable Guy, stage name of American comedian Daniel Lawrence Whitney
• Larry (cartoonist), British cartoonist

Information technology

• Larry Ellison, co-founder of Oracle Corporation
• Larry Page, co-founder of Google
• Larry Sanger, co-founder of Wikipedia
• Larry Wall, creator of the Perl computer language

Politics and law

• Larry Bakman, American attorney
• Larry Craig, former US senator from Idaho
• Larry Hogan (born 1956), former Governor of the U.S. state of Maryland
• Larry C. Johnson, former CIA intelligence officer and political commentator
• Larry Kelly (born c. 1935), American politician
• M. Larry Lawrence, U.S. Ambassador to Switzerland
• Larry Neufeld, Canadian politician
• Larry O'Brien (1917–1990), American politician and basketball commissioner
• Larry Ribstein (1946–2011), American law professor
• Larry Sanders (politician) (born 1935), American-born British academic, social worker and Green Party activist, brother of Bernie Sanders

Sports

Criminals

• Larry Gene Ashbrook, mass murderer
• Larry Gene Bell, American murderer and possible serial killer
• Larry Eyler, American serial killer and kidnapper
• Larry Dewayne Hall (born 1962), American murderer, rapist, and possible serial killer
• Larry Hoover, gang leader
• Larry Eugene Phillips, Jr., bank robber and leader of the High Incident Bandits
• Larry Lawton, American author and ex-convict
• Larry Nassar (born 1963), American serial child molester
• Larry Pusateri, American fugitive
• Larry Ralston (born 1949), American serial killer and rapist
• Larry Ray (born 1959), American criminal convicted of sex trafficking, extortion, forced labor, and other offenses, sentenced to 60 years in prison
• Larry Singleton, rapist and mutilator
• Larry Slack, American child abuser

Multiple individuals

• Larry Brown (disambiguation)
• Larry Gordon (disambiguation)
• Larry Harris (disambiguation)
• Larry Johnson (disambiguation)
• Larry Miller (disambiguation)
• Larry Murphy (disambiguation)
• Larry Phillips (disambiguation)
• Larry Scott (disambiguation)
• Larry Smith (disambiguation)

Other

• Larry Wu-Tai Chin, Chinese double agent who worked in the CIA
• Larry Dossey (born 1940), Texas internist and author
• Larry Flynt (1942–2021), American publisher
• Larry Gbevlo-Lartey, Ghanaian soldier and businessman
• Larry L. Greenfield, educator
• Larry Gene Heien (1937–1991), American linguist
• Larry Huggins, (born c. 1950), president of Riteway-Huggins Construction Services
• Larry Koroloff (born 1951), Bulgarian historian and educator
• Larry Kosilla, American businessman and YouTuber
• Larry Lemanski, director of the Biomedical Institute for Regenerative Research
• Larry A. Nagahara, American physicist, member of the National Cancer Institute
• Larry Reed, American shadow puppeteer
• Larry Sass, architectural designer
• Larry J. Seidman (1950–2017), American neuropsychologist
• Larry Stylinson, a name blended fandomship of musicians Harry Styles and Louis Tomlinson
• Larry Thibos, American scientist and academic
• Larry Wijeratne (1950–1998), Sri Lankan Sinhala army major general
• Lost Boy Larry, nickname for a presumed missing boy in Albuquerque, New Mexico, whose cries for help were broadcast over CB radio for several days in August 1973 (later deemed a hoax by state authorities)

Animation

• Larry the Cucumber, character from VeggieTales; also goes by the alter-ego of Larryboy
• Larry the Lobster, a fictional lifeguard on SpongeBob SquarePants
• Larry Palaroncini, character from Homestar Runner that plays in the band Limozeen
• Larry, an anaconda from the 2006 Disney animated film The Wild
• Larry Burns (The Simpsons), the son of Mr. Burns, portrayed by Rodney Dangerfield in The Simpsons
• Larry, a white mouse who appeared in two episodes of Pinky and the Brain
• Lawrence "Larry", an idiotic crocodile who appears in the Pearls Before Swine comic strip
• Lawrence "Larry" Needlemeyer, a character from The Amazing World of Gumball, who works every job in the fictional city in Elmore.

Movies and television

• Doctor Laurence Erhardt, one of the original mad scientists from Mystery Science Theater 3000 TV series
• Larry, a character in the 1986 American science fiction movie Howard the Duck
• Larry, a character in the 1990 American action comedy movie Kindergarten Cop
• Larry, a character played by Christopher Lloyd in the 1983 American comedy movie Mr. Mom
• Larry, a character in the 2012 American comedy film This Is 40
• Larry, a character in the 2002 monster comedy action film Eight Legged Freaks
• Larry, a character on the American sitcom television series Newhart
• Larry Appleton, a character on the American sitcom television series Perfect Strangers, often referred to as Cousin Larry (1986–1993)
• Larry Blaisdell, character played by Larry Bagby III on Buffy the Vampire Slayer
• Lawrence "Larry" Buckman, a character in the 1989 American family comedy-drama movie Parenthood
• Larry Daley, a character from the Night at the Museum franchise.
• Larry Dallas, Jack Tripper's best friend from the ABC sitcom Three's Company (1977–1984)
• Larry Donner, a character played by Billy Crystal in the 1987 movie Throw Momma from the Train
• Larry Emdur, a host on the Morning Show, Channel 7, Australia
• Larry Fleinhardt, a character who is a theoretical physicist, cosmologist, and CalSci professor in the CBS crime drama NUMB3RS, played by Peter MacNicol
• Larry Howard, a character in the 1986 American science fiction adventure movie Flight of the Navigator
• Larry "Bud" Melman, recurring character on David Letterman shows
• Larry Potter, a character from the American TV sitcom Get a Life (1990–1992)
• Larry Sanders, titular character on the American sitcom The Larry Sanders Show (1992–1998)
• Larry Tate, on the TV series Bewitched
• Larry the Barista, a minor character in the 2014 movie The Lego Movie
• Larry the cameraman, a character played Chris Elliott by in the 1993 American fantasy comedy Groundhog Day

Video games

• Larry Butz, the friend of Phoenix Wright in the Ace Attorney series
• Larry "Pixy" Foulke, a character in Ace Combat Zero: The Belkan War
• Larry Laffer, a character from the Leisure Suit Larry adult video game series
• Larry Koopa, one of the Koopalings in the Super Mario Bros. series
• Larry, a Gym Leader and Elite Four member from Pokémon Scarlet and Violet