Khamis is both a surname and a given name. Notable people with the name include:
Surname:
- Abubaker Kaki Khamis (1989–2025), Sudanese Olympic middle-distance runner
- Ahmed Khamis (born 1985), Emirati football player
- Buku Khamis (born 2000), South Sudanese-Australian rules footballer
- Imad Khamis (born 1961), Syrian politician
- Johnny Khamis, American politician
- Leena Khamis (born 1986), Australian football player
- Mwajuma Hassan Khamis, Tanzanian politician
- Salem Khamis (born 1980), United Arab Emirates football player
- Sham Khamis (born 1995), Australian football player
- Vuai Abdallah Khamis (born 1960), Tanzanian politician
- Younis Khamis (born 1982), United Arab Emirates basketball player
Given name:
- Khamis Gaddafi (1983-2011) son of Muammar Gaddafi
This page or section lists people that share the same given name or the same family name.
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