Surname

• Andreas Gruber (director) (born 1954), Austrian film director and screenwriter
• Andreas Gruber (footballer) (born 1996), Austrian footballer
• Barbara Gruber (born 1977), German ski mountaineer
• Christoph Gruber (born 1976), Austrian alpine skier
• David Gruber, American marine biologist
• Edmund L. Gruber (1879–1941) US Army general, composer of military music, and brother of William R. Gruber
• Fabio Gruber (born 2002), Peruvian footballer
• Ferry Gruber (1926–2004), Austrian-German tenor in opera and operetta
• Florian Gruber (born 1983), German racing driver
• Frank Gruber (1904–1969), writer of Westerns and detective fiction
• Franz Gruber (actor) (born 1930), actor, played in the Japanese Tokusatsu movie/TV productions
• Franz Xaver Gruber (1787–1863), Austrian teacher, composer of "Silent Night"
• Gabriel Gruber (1740–1805), Viennese Jesuit, architect and hydraulics expert
• Gary Gruber (1940–2019), scientist, educator, author
• Gerhard Gruber (born 1951), Austrian pianist
• Hans Gruber (conductor) (1925–2001), Canadian conductor
• Hans Gruber (footballer) (1905–1967), German footballer
• Heinz Karl Gruber (born 1943), Austrian composer (a descendant of Franz Xavier)
• Hendrik Gruber (born 1986), German pole vaulter
• Howard Gruber (1922–2005), professor of psychology of creativity
• Ira D. Gruber (1934–2025), American author, bibliographer, and military historian
• Jeremy Gruber (born 1971), Jewish-American civil rights activist
• Johann Gottfried Gruber (1774–1851), German literary historian and critic
• John Gruber (born 1973), American software engineer, co-developer of Markdown, and blogger (Daring Fireball)
• Jonathan Gruber (economist), American academic, educator; Patient Protection and Affordable Care Act co-architect
• Jonathan Gruber (filmmaker) (Follow Me: The Yoni Netanyahu Story)
• J. Mackye Gruber, American screenwriter
• Jordan Gruber (born 1983), American-Israeli soccer player
• Juan García Gruber (1904–1997), Venezuelan economist, financier, writer, philosopher and diplomat
• Juliette Gruber (born 1965), British actress
• Karl Gruber (1909–1995), foreign minister of Austria from 1945 to 1953
• Kelly Gruber (born 1962), U.S. Major League Baseball player
• Kurt Gruber (1904–1943), Nazi politician
• Kurt Gruber (aviator) (1896–1918), Austro-Hungarian flying ace
• Lilli Gruber (born 1957), Italian television journalist and politician
• Malvina Gruber (born 1900), Czech Jewish Comintern agent
• Martin Gruber (disambiguation), multiple people
• Michael Gruber (actor) (born 1964), American actor
• Michael Gruber (author) (born 1940), American novelist
• Mieczyslaw Gruber (1913–2006), Jewish resistance fighter
• Patrick Gruber (born 1978), Italian luger
• Paul Gruber (born 1965), professional football player for the Tampa Bay Buccaneers (1988–1999)
• Rony Gruber (born 1963), movie director and scriptwriter.
• Ruth Gruber (1911–2016), Jewish-American journalist and author of "I visited the Soviet Arctic"
• Samuel D. Gruber (born 1956), American architecture historian, specialist on Jewish sites
• Samuel H. Gruber (1938–2019), shark biologist
• Scarlet Gruber (born 1989), Venezuelan actress
• Stefan Gruber (born 1975), performance artist, animator and educator
• Theodor Gruber, Austrian chess player
• Tom Gruber (born 1959), American computer scientist, inventor, and entrepreneur
• William H. Gruber (born 1935), American organizational theorist
• William R. Gruber (1890–1979), United States Army brigadier general
• William C. Gruber, American physician-scientist, pediatrician, and business executive
• William Gruber, organ maker and inventor of the View-Master stereoscopic system

Nickname

(See also the longer list at de:wiki)

• Dave "Gruber" Allen (born 1958), American comedian and actor