Film, television, and theatre

Gaming

• Defender (card player), a player who plays against the declarer
• Defender (1981 video game)
• Defender (2002 video game), a remake
• Defender, a 1982 pinball table based on the 1981 video game.

Literature

• The Chicago Defender , a Chicago-based online newspaper
• Defender, a 2001 novel in C. J. Cherryh's Foreigner series
• The Defender (Kalashnikoff novel), a 1951 novel by Nicholas Kalashnikoff
• The Defender (Thwaites novel), a 1936 novel by F. J. Thwaites
• Defenders (comics), a fictional superhero group in Marvel comic books
• "The Defenders" (short story), a 1953 short story by Philip K. Dick

Music

• Defender (album), a 1987 album by Rory Gallagher
• "Defender" (Gabriella Cilmi song), 2010
• "Defender" (Peter Andre song), 2010
• "The Defender", a 1982 song by Buckner & Garcia from Pac-Man Fever
• "Defender", a 1987 song by Manowar from Fighting the World
• "Defender", a 2012 song by As I Lay Dying from Awakened
• "Defender", a 2020 song by August Burns Red from Guardians
• "Defenders", a 2014 song by DragonForce from Maximum Overload

Aircraft

• Britten-Norman Defender, a multi-role utility transport aircraft
• Fletcher FD-25 Defender, a 1950s American light ground-attack aircraft
• McDonnell Douglas MD 500 Defender, a light military helicopter

Naval and Coast Guard vessels

• HMS Defender, the name of several ships of the Royal Navy
• USS Defender (MCM-2), a mine countermeasures ship of the U.S. Navy
• Defender-class boat, a class of boat of the U.S. Coast Guard
• Defender-class torpedo boat (1883)