De Los Santos, also spelled delos Santos in the Philippines, is a Spanish surname meaning "of the saints". Notable people with the surname include:

• Abel De Los Santos (born 1992), American baseball player
• Alejandro de los Santos (1902–1982), Argentinian football player
• Alfredo de los Santos (disambiguation), multiple people
• Enyel De Los Santos (born 1995), Dominican Republic baseball player
• Epifanio de los Santos (1871–1928), Filipino historian
• Fautino de los Santos (born 1986), Dominican Republic baseball player
• Gonzalo de los Santos (born 1976), Uruguayan football player
• Jaime de los Santos (born 1946), Filipino general
• Ramón de los Santos (1949–2015), Dominican Republic baseball player
• Valerio de los Santos (born 1972), Dominican Republic baseball player
• William de los Santos, (born 1964), actor
• Yerry De Los Santos (born 1997), Dominican baseball player
• Luis de los Santos (first baseman), Dominican baseball player
• Luis De Los Santos (third baseman), Dominican baseball player

See also

• 33219 De Los Santos, an asteroid
• Epifanio de los Santos Avenue

Surname list

This page lists people with the surname De Los Santos.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.