Cottonmouth may refer to:

Contents

• Vipers
• Medical symptom
• Arts and entertainment
• Fictional characters and elements
• Music
• Television
• Technology

Vipers

• Agkistrodon piscivorus (northern cottonmouth), a semiaquatic pit viper found in the southeastern United States.
• Agkistrodon conanti (Florida cottonmouth), a semiaquatic pit viper found on the Florida peninsula and southern Georgia.

Medical symptom

• Xerostomia, or dry mouth, a medical symptom

Arts and entertainment

Technology

• COTTONMOUTH, a modified USB cable used for espionage by the National Security Agency

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