| Men's singles | |
|---|---|
| 2021 Mubadala World Tennis Championship | |
| Champion |  Andrey Rublev |
| Runner-up |  Andy Murray |
| Score | 6–4, 7–6(7–2) |
Rafael Nadal was the defending champion [1] [2] but lost in the semifinals to Andy Murray.
Andrey Rublev won the title, defeating Murray in the final.
Andrey Rublev (champion)
Rafael Nadal (semifinals) (fourth place)
Denis Shapovalov (semifinals) (third place)
Taylor Fritz (quarterfinals) (fifth place) Dan Evans (quarterfinals) (sixth place) Andy Murray (final) (runner-up)Key
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | Andrey Rublev | 77 | 3 | 6 | ||||||||||||||||
| 3 | Denis Shapovalov | 65 | 6 | 4 | ||||||||||||||||
| 3 | Denis Shapovalov | 6 | 6 | |||||||||||||||||
| 4 | Taylor Fritz | 3 | 0 | |||||||||||||||||
| 1 | Andrey Rublev | 6 | 77 | |||||||||||||||||
| 6 | Andy Murray | 4 | 62 | |||||||||||||||||
| 5 | Dan Evans | 3 | 2 | |||||||||||||||||
| 6 | Andy Murray | 6 | 6 | |||||||||||||||||
| 6 | Andy Murray | 6 | 7 | Third Place Match | ||||||||||||||||
| 2 | Rafael Nadal | 3 | 5 | |||||||||||||||||
| 3 | Denis Shapovalov | 64 | 6 | [10] | ||||||||||||||||
| 2 | Rafael Nadal | 77 | 3 | [6] | ||||||||||||||||
| Fifth Place Match | ||||||
| 4 | Taylor Fritz | 77 | 4 | [11] | ||
| 5 | Dan Evans | 65 | 6 | [9] | ||
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