| Singles | |
|---|---|
| 2001 Campionati Internazionali di Sicilia | |
| Champion | |
| Runner-up | |
| Score | 7–6(7–2), 6–4 |
| Draw | 32 |
| Seeds | 8 |
Olivier Rochus was the defending champion but did not compete that year.
Félix Mantilla won in the final 7–6(7–2), 6–4 against David Nalbandian.
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.
Key